I am interested in developing nano technologies for diagnostic and prognostic cancer imaging and translating them into clinic practice.  Multiplexed immuno-staining with Qdots provides us with a nice approach to profile a panel of cancer biomarkers for any single specimen from patients. Therefore, it allows a much more reliable diagnosis than conventional methods.  My projects will help both the doctors and patients by establishing links between the fingerprints of cancer biomarkers and clinic outcomes.  In addition, I am working with my colleagues in Nie group to develop robust methods of bioconjugation for nano particles.

My research interests include fundamental understanding of nano- materials, development, and applications of microfabricated devices.

Publications and Presentation

Publications:
Liu, J., Enzelberger, M., Quake, S.R., A nanoliter rotary device for polymerase chain reaction, Electrophoresis, 23(10), 1531-1536, 2002.

Liu, J., Hansen, C., Quake, S.R., Solving the world-to-chip interface problem with a microfluidic matrix, Analytical Chemistry, 75(18), 4718-4723, 2003.

Liu, J., Williams A.B., Gwirtz, R.M., Wold, B.J., Quake, S.R., Enhanced signals and fast nucleic acid hybridization using microfluidic chaotic mixing, Angew. Chem. Int. Ed. 45, 3618-3623, 2006.

Spletter, M.L., Liu, J., Su, H., Giniger, E., Komiyama, T., Quake, S., Luo, L., Lola regulates Drosophila olfactory projection neuron identity and targeting specificity, Neural Development, 2(14), 2007

Presentations:
IEEE LEOS Annual Meeting, Orlando, FL (October, 2007).

Biophysical Society Annual Meeting, Long Beach, CA (February, 2005).

Smalltalk2003 Conference, San Jose, CA (July, 2003).

IBC BioMEMs and Microfluidics Conference, San Diego, CA (April, 2003).

Material Research Society (MRS) Spring Meeting, San Francisco, CA (April, 2002)

One device was featured in the cover of Engineering and Science (Volume LXVI, Number 2, 2003).

Association of Laboratory Automation (ALA) Travel Fellowship (2003).

Dow Travel Award (2002~2003).